FASCINATION ABOUT NAD+ SUPPLEMENTS FOR ENERGY AND METABOLISM

Future, we handled cells with different concentrations of NAD+. When added for 24 h at 80 µM in HeLa and 400 µM in U2OS cells, NAD+ impaired the incorporation of EdU (Fig. 2a and Prolonged Information Fig. 1k,l). Also, sixteen µM of NAD+ was ample to cut back fork pace by ~40% in HeLa cells without having influencing the entire standard